Usage: *For complete product information, please review the full prescribing information in the manufacturer package insert. Manufacturer Dosage and Administration: SENTINEL FLAVOR TABS are given orally, once a month, at the recommended minimum dosage of 0.23 mg⁄lb (0.5 mg⁄kg) milbemycin oxime and 4.55 mg⁄lb (10mg⁄kg) lufenuron. For dogs over 100 lbs., administer the appropriate combination of tablets. SENTINEL FLAVOR TABS are palatable, and most dogs will consume the tablet when offered by the owner. As an alternative to direct dosing, the tablets can be hidden in food. Be certain the dog consumes the entire tablet or tablets. Administer SENTINEL FLAVOR TABS to dogs immediately after or in conjunction with a normal meal. Food is essential for adequate absorption of lufenuron. Watch the dog closely following administration to be sure the entire dose has been consumed. If it is not entirely consumed, redose with the full recommended dose as soon as possible. SENTINEL FLAVOR TABS must be administered monthly, preferably on the same date each month. Treatment with SENTINEL FLAVOR TABS may begin at any time of year. In geographic areas where mosquitoes and fleas are seasonal, the treatment schedule should begin one month prior to the expected onset and should continue until the end of "mosquito and flea season." In areas with year–round infestations, treatment should continue through the entire year without interruption. If a dose is missed and a 30–day interval between dosing is exceeded, administer SENTINEL FLAVOR TABS immediately and resume the monthly dosing schedule. If SENTINEL FLAVOR TABS replace daily diethylcarbamazine (DEC) for heartworm prevention, the first dose must be given within 30 days after the last dose of DEC.
Missed Doses: If a dose is missed: give SENTINEL FLAVOR TABS immediately to resume monthly dosing and notify your veterinarian. Do not give two doses at once. If multiple doses have been missed, consult your veterinarian prior to restarting the monthly dosing schedule.
Side Effects: SENTINEL FLAVOR TABS are generally well tolerated, and side effects are considered uncommon when given at the recommended dosage. Reported side effects include (but may not be limited to) vomiting, depression⁄lethargy, itching, skin reactions (e.g., redness, rash), diarrhea, decreased appetite, decreased coordination, salivation⁄drooling, and weakness. Contact your veterinarian immediately if your pet experiences a shock–like reaction, severe or persistent vomiting, excessive drooling, fainting⁄collapse, or if you notice your pet has a seizure, extreme weakness⁄tiredness, dilated pupils, or severely decreased coordination (e.g., stumbling, difficulty walking). Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome. If you notice anything unusual, please consult your veterinarian.
Precautions: *For complete product information including warnings and precautions, please refer to the manufacturer package insert. For oral use in dogs only– not for use in humans. Keep this and all drugs out of the reach of children. Do not use in puppies less than four weeks of age and less than two pounds of body weight. Prior to administration of SENTINEL FLAVOR TABS, dogs should be tested for existing heartworm infections. Infected dogs should be treated to remove adultheartworms and microfilariae prior to initiating treatment with SENTINEL FLAVOR TABS. Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy have been noted in some treated dogs carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. SENTINEL FLAVOR TABS immediately break the flea life cycle by inhibiting egg development. However, preexisting flea populations may continue to develop and emerge after treatment with SENTINEL FLAVOR TABS has begun. Based on results of clinical studies, this emergence generally occurs during the first 30–60 days. Therefore, noticeable control may not be observed until several weeks after dosing when a preexisting infestation is present. Cooler geographic areas may have longer lag periods due to a prolonged flea life cycle. The concurrent use of an approved adulticide may be employed depending on the severity of the infestation. If a SENTINEL FLAVOR TABS–treated dog comes in contact with a flea–infested environment, adult fleas may infest the treated animal. These adult fleas are unable to produce viable offspring. The temporary use of an adulticide product may be necessary to kill these adult fleas. The safety of SENTINEL FLAVOR TABS has not been established and should be used with caution in breeding, pregnant, or lactating dogs. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups. Do not administer to animals with a known history or suspected allergy⁄hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention.
