DESCRIPTION: Mexiletine is used to treat ventricular arrhythmia. This antiarrhythmic is a sodium channel-blocking medication (class 1B).
Key Benefits:
Mexiletine is approximately 85% bioavailable, and it is well-absorbed through oral administration. The liver partially metabolizes the medication and excretes that 10% through the animal's feces, and the remainder is eliminated through the urine. Animals with acute myocardial infarction, hepatic dysfunction, severe kidney disease, or reduced cardiac output may experience a longer half-life.
Formulated For: For dogs only.
How is Medication Given? Follow your veterinarian's directions when using this product.
What Results Can I Expect? Mexiletine Features:
Positive treatment response is indicated by 85% reduction in premature ventricular contractions Can be used to treat Boxers with inherited cardiomyopathy and Doberman Pinschers with dilated cardiomyopathy Is similar in nature to Lidocaine Can be used concomitantly with Atenolol or Sotalol in cases where monotherapy is insufficient Treats PVCs, ventricular tachycardia, and other ventricular arrhythmias
What Form Does Medication Come In? Capsules
Dose and Administration: Capsules are sold individually in 150, 200, or 250 mg strengths.
Possible Side Effects: The most common side effects are nausea, vomiting, and other gastrointestinal effects. Administering with food can mitigate this response. Other potential side effects are related to the central nervous system, such as:
Dizziness Imbalance Trembling Shortness of Breath Cardiac Signs (PVCs or Chest Pain)
Precautions: Use with caution in any animal with:
Second or Third Degree AV Heart Block Abnormal Intraventricular ConductionAbnormal Sinus Node Function Cardiogenic Shock Congestive Heart Failure Myocardial Infarction Liver Dysfunction Hypotension Seizure Disorders
Storage Recommendations: Store at room temperature.
