DESCRIPTION: Piroxicam is an NSAID (non-steroidal anti-inflammatory drug) that is useful in treating certain cancers in dogs and cats. It is also sometimes used to treat osteoarthritis-related pain and inflammation.
Key Benefits:
Piroxicam is an NSAID (non-steroidal anti-inflammatory drug). This non-selective COX (cyclooxygenase inhibitor) has an inhibitory effect on both COX-1 and COX-2. COX-1 is responsible for the production of prostaglandins that regulate homeostasis and help the kidneys respond to hypotension and protect the gastrointestinal tract. COX-2 is responsible for producing prostaglandins, which increase when inflammation is present. This receptor is upregulated in the case of certain tumors, including nasal epithelial tumors, mammary tumors, oral melanoma, oral squamous cell carcinoma, colorectal tumors, prostatic carcinoma, TCC (urinary bladder transitional cell carcinoma), and osteosarcoma.
Formulated For: Intended for cats and dogs.
How is Medication Given? Follow your veterinarian's directions when using this product.
What Results Can I Expect? Piroxicam:
Can be used as concomitant treatment for treating bladder cancer (transitional cell carcinoma) Acts as an anti-inflammatory and pain relief medication for cats Treats chronic rhinitis in dogs and cats Is effective in reducing fevers
What Form Does Medication Come In? Capsules
Dose and Administration: Capsules are sold individually in a single strength (20 mg).
Possible Side Effects: Potential side effects include:
Stomach ulcers and bleeding Intestinal ulcers and bleeding Dark or tarry stools (associated with intestinal bleeding) Vomiting Inappetence Peritonitis associated with intestinal perforation Ulcers (particularly when administered concomitantly with cortisone, prednisone, other corticosteroids, aspirin, or phenylbutazone) Sudden onset of serious kidney injury (papillary necrosis) Decreased kidney function Impaired blood clotting associated with blood platelet effects Liver injuries associated with elevated liver enzymes (a potential side effect of all NSAIDs)
Some side effects can appear suddenly and become life-threatening.
Precautions:
Keep away from children and animals. Never use in hypersensitive or allergic animals. Do not administer to animals with bleeding, inflammation, stomach perforation, mucosa (intestinal lining) perforation, or high blood pressure. Administer with caution to animals with heart failure. Tell your vet about all other medications your pet is taking to rule out potential interactions. Drug interactions are known to occur with concomitant diuretic or ACE inhibitor (Enalapril, Benazepril, and Quinapril) use.
Storage Recommendations: Store in a cool and dry location.
In Case of Overdose:Contact the nearest emergency pet clinic immediately.
