Usage: *For complete product information, please review the full prescribing information in the manufacturer package insert. Vetoryl Capsules for Dogs should be given orally as directed by your veterinarian. Wash your hands thoroughly with soap and water after handling the medication. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule. Vetoryl Capsules should be administered with food. Capsules should be kept sealed in their original packaging until administration and should not be broken, split, or opened. Your veterinarian may need to perform bloodwork and⁄or monitor your pet closely while taking this medication. Do not miss any follow–up visits.
Missed Doses: Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.
Side Effects: Vetoryl is generally well tolerated in dogs. The most common side effects of this medication are an unexpected decrease in appetite, vomiting, diarrhea, and lethargy. Discontinue Vetoryl Capsules and contact your veterinarian immediately if any signs of intolerance are observed, including vomiting, diarrhea, lethargy, poor⁄reduced appetite, weakness, or collapse. A potentially life–threatening medical emergency known as an Addisonian crisis can occur if cortisol levels become critically low. Seek emergency veterinary care immediately if any signs of this are observed, including pale gums, weakness or collapse, or severe⁄bloody vomiting or diarrhea. Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome. If you notice anything unusual, please consult your veterinarian.
Precautions: *For complete product information including warnings and precautions, please refer to the manufacturer package insert. For oral use in dogs only– not for human use. Keep out of reach of children. Wash hands after use. Do not empty capsule contents and do not attempt to divide the capsules. Do not handle the capsules if pregnant or if trying to conceive. Trilostane is associated with teratogenic effects and early pregnancy loss in laboratory animals. In the event of accidental ingestion⁄overdose, seek medical advice immediately and take the labeled container with you. Do NOT use Vetoryl Capsules in animals with primary hepatic disease or renal insufficiency. Do NOT use in pregnant dogs. Studies conducted with trilostane in laboratory animals have shown teratogenic effects and early pregnancy loss. The safe use of this drug has not been evaluated in lactating dogs and males intended for breeding. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups. All dogs should undergo a thorough history and physical examination before initiation of therapy with Vetoryl Capsules. Owners should be advised to discontinue therapy immediately and contact their veterinarian if signs of potential drug toxicity are observed. Do not administer to animals with a known history or suspected allergy⁄hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.
Drug & Food Interactions: The following drugs* may have potential interactions with this medication: ACE inhibitors (e.g., benazepril, enalapril), ARBs (e.g., telmisartan), ketoconazole, mitotane, potassium–sparing diuretics (e.g., spironolactone), potassium salts (e.g., potassium bromide, potassium citrate), and potassium supplements. *NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together. Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.
Overdose: If you have any reason to suspect an overdose, call your doctor⁄veterinarian or the appropriate poison control resource immediately. For humans: The national toll–free Poison Help line, 1–800–222–1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories. For animals: The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888–426–4435. Pet Poison Helpline® also provides a 24⁄7 animal poison control service at 855–764–7661. *Please note: this information is for third–party services and is provided for convenience in case of potential poison–related emergencies. There may be consultation fee for these services.
Storage: Store in a cool, dry place at a controlled room temperature (77°F), with excursions permitted between 59 and 86°F. Keep the medication sealed in its original packaging and out of the reach of children and pets. Do not puncture foil and expose capsules until it is time for administration. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.
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