Pentosan Polysulfate 250 mg/ml, 6 ml
DESCRIPTION: Pentosan Polysulfate works to temporarily coat and replenish the glycosaminoglycan (GAG) layer of the urinary bladder. GAGs are responsible for protecting the bladder against urinary agents. This sterile, injectable product also treats osteoarthritis. Key Benefits: PPS, or Pentosan Polysulfate, is a heparin-like, semi-synthetic type of polysaccharide ester. It is a beechwood hemicellulose derivative, and it is a mild anticoagulant with anti-inflammatory, fibrinolytic, and hypolipidemic properties. It is used to manage and treat osteoarthritis. It is thought to help preserve cartilage integrity, which improves joint health by supporting chondrocyte and synoviocyte anabolic activity. It protects the joints against catabolic events by reducing inflammatory mediators and cytokine levels in the cartilage matrix and synovial fluid. Formulated For: Intended for horses, cats and dogs only. How is Medication Given? Follow your veterinarian's directions when using this product. What Results Can I Expect? Pentosan Polysulfate coats and replenishes the glycosaminoglycan (GAG) layer of the urinary bladder. It is an effective osteoarthritis treatment option. What Form Does Medication Come In? Injectable Dose and Administration: Sold in a vial containing 6 mL (250 mg per mL). Possible Side Effects: This medication is generally well-tolerated, but potential adverse reactions include: In Horses: Elevated PTT (partial thromboplastin time), lasting 24 hours or less Intra-articular bleeding (with intra-articular administration) In Dogs: Vomiting Anorexia Mild gastrointestinal reactions Precautions: Keep away from children and animals. Remove and wash contaminated clothing before reuse. Wear protective gloves, protective clothing, eye protection, and face protection when handling. In case of skin contact, wash thoroughly using plenty of water. If the skin becomes irritated, pursue medical treatment. Wash hands thoroughly after handling. Not FDA-approved. Storage Recommendations: Store in a cool and dry location. In Case of Overdose: Contact the nearest emergency pet clinic. Active Ingredients: 250 mg/mL Pentosan Polysulfate Sodium Main Ingredients: 250 mg/mL Pentosan Polysulfate SodiumView details
Zycosan (Pentosan Polysulfate Sodium) Injection - 250 mg/mL, 7.5 mL vial
Zycosan Injectable Solution - 7.5 mL, 4 Vials
Description: Zycosan is indicated for the control of clinical signs associated with osteoarthritis in horses. Product: Zycosan (pentosan polysulfate sodium injection) For: Horses Generic Name: Pentosan Polysulfate Brand Names: Zycosan Injection Drug Class: Anti inflammatory, Osteoarthritis Disease Modifier Manufacturer: Dechra Product Description & Form: Zycosan 250 mg ml Injection 7.5 ml Vial (4 Count): Pale yellow to brownish yellow, clear, sterile solution. (NDC 17033 0461 75) Zycosan 250 mg ml Injection 7.5 ml Vial (4 Count) Benefits: Helps control the clinical signs associated with osteoarthritis Product contains 4 x 7.5 ml single use vials Thought to include stimulation of hyaluronic acid and glycosaminoglycan synthesis in damaged joints, inhibition of proteolytic enzymes, and scavenging of damaging free radicals Does not contain a preservative and unused portions should be discarded First and only injectable pentosan product for horses to be evaluated and approved by the standards of the FDA Active Ingredients: Pentosan polysulfate sodium Usage: Zycosan should be administered as directed by your veterinarian. May cause skin irritation. Wear gloves and wash hands thoroughly after administration. Use aseptic techniques when withdrawing each dose to decrease the possibility of post injection bacterial infections. Adequately clean and disinfect the stopper prior to entry with a sterile needle and syringe.Injectable medications require needles and syringes. Those items are purchased separately. Please ask your veterinarian for a recommendation for the correct needle syringe sizes for your pet.Use only sterile needles syringes and use each needle syringe only once. Dispose the needle syringe immediately in a proper sharps disposal container. Sharps containers are sold separately. Injectable medications require needles and syringes. Those items are purchased separately. Please ask your veterinarian for a recommendation for the correct needle syringe sizes for your pet. Discard any unused portion of vial contents after initial use. Discard any unused portion of vial contents after initial use. Missed Doses: Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once. Side Effects: Side effects are not expected to occur with normal doses. Injection site reactions may occur. If you notice anything unusual, contact your veterinarian. Drug & Food Interactions: Use caution when combining with other medications that may interfere with blood clotting, NSAIDS or other anticoagulants, dexamethasone, prednisone, prednisolone, or triamcinolone. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together. Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and or monitor your pet more closely. Cautions: Not for use in humans. Zycosan has been shown to prolong coagulation parameters up to 24 hours after injection, therefore caution should be used when administering this drug before or after strenuous activities. Due to the anticoagulant effects, this drug may exacerbate Exercise Induced Pulmonary Hemorrhage (EIPH). The concurrent use of NSAIDs with Zycosan has not been evaluated. Due to the anticoagulant effects of Zycosan and known anticoagulant effects of some NSAIDs, caution should be used if NSAIDs are concurrently administered. Horses concurrently treated with Zycosan and NSAIDs should be monitored for hemorrhage or other clinical signs of abnormal bleeding (e.g., petechiae, ecchymosis, or epistaxis). Pentosan polysulfate sodium is a weak anticoagulant. Caution should be used when administering Zycosan if you are taking an anticoagulant. In case of accidental self injection, seek immediate medical attention. If product comes into contact with skin, rinse skin thoroughly with water and seek medical attention if needed. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; widespread hives and itching. Adverse Reactions: If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Dechra at 866 933 2472 or Vetsource customer service at 877 738 4443. Storage: Store at 68 F to 77 F in controlled room temperature, excursion permitted between 59 F to 86 F. Do not freeze. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture. Sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer. Sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.View details
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